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BPC-157 (Body Protection Compound-157, Arginine Salt Form) BPC-157 is a 15-amino acid synthetic peptide derived from a protective protein found naturally in human gastric juice
With the lung infiltration of neutrophils and macrophages triggered by CS, proinflammatory cytokines such as interleukin -1(IL-1) and tumor necrosis factor- (TNF-) induce a cascade of amplification effects of inflammation, and activate nuclear factor- B (NF- B) (Di Stefano et al., 2002)
Treatment with FOXO4-DRI following chemotherapy exposure potently counteracts these effects, normalizing body weight and reducing plasma AST to near-baseline levels