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When leg muscle mass declines, as can happen on GLP-1 therapy without adequate protein or exercise, insulin sensitivity can paradoxically worsen even as body weight falls

Ozempic (semaglutide) is a GLP-1 receptor agonist with a one-week half-life, meaning overdose effects may persist for several days

Severe Pain A standard injection-site bruise might be slightly tender if you press on it, but it should not cause throbbing or sharp pain that interferes with your daily life

Always consult with your healthcare provider before starting any new medication, particularly if you have had your gallbladder removed or have other health conditions