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on the contrary, the amount of the lipid peroxidation product malondialdehyde increased in the same tissue (Bosch-Morell et al., 2009, 2011) have confirmed significant increased levels of lipid peroxidation and marked decrease in GSH, superoxide dismutase and catalase activities in the sciatic nerve of rats which were given alcohol for 10 weeks

Whittaker, R.H

However, metformin also exerts anticancer effects and is thought to do this through both AMPK-dependent and AMPK-independent mechanisms 116