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Bernink FJ, Timmers L, Diamant M, et al

11 However, achieving and maintaining this degree of weight loss is challenging, making pharmacologic and procedural interventions essential tools in clinical practice

I actually got a little too thin and spent a few months gaining back a bit of weight

N Engl J Med 326:22, 1992 The effect of impaired glucagon suppression on plasma glycemia is dependent on insulin Glucagon Glucagon Insulin Non-diabetic Diabetic HGP Glucose Glucose HGP Non-diabetic Diabetic AJP 277:E283;1999 Placebo Exenatide 0.10 g/kg sc 0 60 120 180 Time (min) Exenatide or placebo Exenatide Reduces Postprandial Glucagon Secretion in Patients With Type 2 Diabetes Meal 200 150 Plasma Glucagon (ng/L) 100 50 0 N = 20.Mean (SE)