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High reaction rates and contributions of glucuronidation and oxidation were observed in the pericentral region, while sulfation was promoted in the periportal region

GHK-Cu has also been detected in saliva and urine, suggesting it is a systemically distributed endogenous peptide rather than a purely circulatory factor

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In our study, we found microglia activation in the hippocampus of APP/PS1 mice after ethanol exposure