Most patients tolerate Semaglutide well over time
Semaglutide is usually started at a lower dose to reduce side effects, then slowly increased
Withdrawal symptoms can include Increased appetite Decreased satiety Elevated blood sugar levels Weight gain Elevated blood pressure and other cardiovascular changes A study from a 2022 clinical trial that tested semaglutide treatment for weight loss found that participants had regained about two-thirds of their initial weight loss on average, and many patients also experienced raised blood pressure levels
doi: 10.3389/fphar.2025.1562896 Received 23 January 2025 Accepted 05 May 2025 Published 02 June 2025 Corrected 09 June 2025 Volume 16 - 2025 Edited by Ahmed Ghallab, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Germany Reviewed by Madlen Matz-Soja, Leipzig University, Germany Mohamed Albadry, University Hospital Jena, Germany Updates Copyright 2025 Sun, Shang, Lv, Liu, Wu and Geng
