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Zonal changes in the rat liver after chronic administration of phenobarbitone in ultrastructural, morphometric and biochemical correlation

Mitochondrial dysfunction in adaptive immune cells Mitochondrial dysfunction has been detected in lupus T cells and is characterized by excessive mROS production, elevated transmembrane potential, downregulated mitophagy, and reduced glutathione levels ( Multiple signaling pathways enable the sequestration and successful clearance of damaged mitochondria by mitophagy, suppressing mtROS accumulation ( 2+ alteration may account for the inappropriate activation in lupus T cells

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