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GIP may also complement the appetite-suppressing effects of GLP-1 and improve fat metabolism

Significant Muscle Loss New research suggests that up to 60% of weight lost on GLP-1 drugs comes from lean muscle mass, which slows metabolism and makes long-term weight maintenance harder

While autophagy is normally a protective mechanism, Erastin subverts this process to promote ferritinophagy, leading to the large-scale degradation of ferritin and the release of excess iron that further reinforces ferroptosis

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