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Note: Market size and forecast figures in this report are generated using Mordor Intelligences proprietary estimation framework, updated with the latest available data and insights as of 2026

Figure 4 In the context of gout, a decrease in BA levels leads to attenuated FXR activity, consequently diminishes the inhibitory effect on NLRP3 and NF-B signaling pathways and promotes enhanced activity and expression of intestinal XOD, thereby triggering inflammatory responses and elevated UA levels, which exacerbate the progression of gout ( Figure 4 )