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This central nervous system activity is what produces the reduction in appetite, food cravings, and the subjective preoccupation with food that many patients describe as "food noise" the background mental chatter about eating that semaglutide substantially quiets

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Antidepressants like Lexapro can raise questions about mood effects, appetite shifts, nausea, or overlapping side effects

The findings showed that 2.4 mg each of semaglutide and cagrilintide resulted in a 23% reduction in body weight, whereas 15 mg of tirzepatide resulted in a 25.5% reduction