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In a post-hoc analysis of LEADER, the use of liraglutide in those with CKD was safe, with no difference in the frequency of serious adverse events between those participants with and without CKD [96]

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Immortalized brown preadipocytes were maintained in DMEM supplemented with penicillin, streptomycin, 10 mM HEPES, 2 mM glutamine and 10% heat-inactivated FBS