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Hydroxocobalamin: Typically administered through B12 injections, this form is produced naturally by bacteria and provides long-lasting effects in the bloodstream

doi: 10.1016/S0736-5748(00)00073-3

Pernicious anemia , where the body cant absorb B12, is a main reason

For instance, NR supplementation in preclinical studies has been shown to reduce chemotherapy-induced peripheral neuropathy, inhibit cancer metastasis, and, in some cases, enhance tumor-suppressive effects. A brief summary of these findings can be found below in the Appendix in Table 1, illustrating that NAD+ metabolism is complex and may be protective under certain conditions