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The cohort included both males and females although the exact sex distribution is not reported, and children with major medical comorbidities were not described beyond gastrointestinal complaints

Their bodies metabolize and eliminate the medication more quickly

Percent change in weight from baseline to week 72 Primary outcome: Results Among participants with obesity but without diabetes, treatment with tirzepatide was superior to treatment with semaglutide with respect to reduction in body weight and waist circumference at week 72

Fibrosis, the excessive deposition of extracellular matrix proteins, is another hallmark of heart failure [88]