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The target maintenance doses are 2.4mg of each peptide gave once weekly on the same day

In the arterial wall, NO promotes vasodilation and maintains the integrity of the vascular endothelial barrier, thereby limiting the harmful translocation of LDL to the arterial intima 34 (Fig

On the molecular level, fisetin acts on multiple signaling pathways, including BCL-2, PI3K/AKT, p53, and NF- B, all of which are critical for senescence

In this model, the deficiency of GPx1 caused excess vascular superoxide and decreased bioavailable nitric oxide, and vascular injury by balloon angioplasty and stenting increased the expression of GSH enzymes, with a corresponding increase in GSH and the GSH/GSSG ratio