glp 1 heart muscle GLP-1 Receptor Agonists in Failure Direct cardiovascular effects of glucagon

For type 2 diabetes , NICE NG28 recommends continuing GLP-1 treatment only if there is adequate response, defined as HbA1c reduction of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at 6 months

Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, et al

Biological activities of essential oils Recent studies on essential oils have highlighted their diverse biological activities, including antimicrobial, antiviral, antihelminthic, antioxidant, antiulcer, anti-inflammatory, insecticidal, larvicidal, and immunomodulatory effects

293,294 YAP can inhibit glucose-6-phosphatase catalytic subunit (G6PC) and phosphoenolpyruvate carboxykinase 1 (PCK1) via peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1), eventually hampering gluconeogenesis