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[33] also evaluated corneal nerve density and length by scan and sweat chloride concentrations and used the questionnaire for neuropathic pain (DN4)

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Contraindications: - Personal or family history of medullary thyroid carcinoma (MTC) - Multiple Endocrine Neoplasia syndrome type 2 (MEN2) - Serious hypersensitivity to orforglipron Safety profile: Common adverse effects include nausea, diarrhea, constipation, vomiting, abdominal pain, and fatigue

From baseline, the mean percentage change in body weight was 11.5, 13.9, and 15.3 percent with 4, 9, and 12 mg of retatrutide, respectively, versus 2.6 percent with placebo