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Altogether, NRF2 is a transcriptional factor of GCLC, and ACTL6A co-works with NRF2 and affects NRF2 binding to the promoter of GCLC, thereby regulates GCLC expression at the transcriptional level

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In the laboratory, mycelia are usually cultivated in a sterilized nutritional medium enclosed in flasks (Brazkova et al., 2022)

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