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The interplay between hydrogen-producing fermentative bacteria and hydrogen consuming reductive acetogens, methanogenic archaea and sulfate-reducing bacteria becomes imbalanced in association with many gut disorders, such as inflammatory bowel disease (IBD), small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS), and colon cancer ( 2 , produced by hydrogenogenic microbes, is severely depleted in deuterium, relative to the levels of deuterium in the molecules from which it was extracted
Additionally, targeting microbial metabolites and immune factors may also be effective in treating neurotraumatic diseases by modulating local immune responses and promoting neuronal recovery
On the contrary significant reduction of GR activity was shown in treated with Cd [20]
PubMed, Ishiguro, Junko, et al
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