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The GABA shunt pathway connects GABA metabolism to the Tricarboxylic Acid cycle (TCA) through GABA, GABA transaminase (GABA-T), and succinic semialdehyde dehydrogenase (SSADH)

The Zn 2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila

39 Additionally, there is established evidence of alterations in glutamate circuits and GABAergic circuits in ASD patients, as manifested by increased numbers of excitatory synapses and spine densities, significantly reduced levels of glutamic acid decarboxylase, and GABAA and GABAB receptor alterations in the postmortem brains of patients with autism

Many genes have several roles in the body, and ACK1 s roles in expression of the androgen receptor and in reigning in the immune system make it an appealing target for cancer therapy, especially against solid tumors with a hormonal growth component, such as prostate and breast cancers