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Curcumin is a polyphenol, which is a type of plant-based micronutrient known for its own antioxidant properties

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Furthermore, in a phase II study, the combination of chemotherapy (albumin-bound paclitaxel and gemcitabine) along with pegvorhyaluronidase alfa (PEGPH20), an agent designed to degrade hyaluronan, has been shown to improve progression-free survival in pancreatic cancer patients, especially those with hyaluronan-high tumors [136]

The shift from Gs to Gq effective coupling in persistently depolarised beta cells may hint at therapeutic and pathophysiological significance