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Pedosphere 31(1):310

Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampus

Advanced Treatments For severe or persistent CIPN, advanced medical interventions may be needed

Specifically, the O1A of adenine phosphate interacts with the NZ of Lys12, the C2 phosphate group of the adenine ribose interacts with the Arg10, His35, and Lys36 side chains, the O2X of adenine phosphate forms hydrogen bonds with the NH2 of Arg10 and the NZ of Lys36, the O3X of adenine phosphate forms hydrogen bonds with the NE2 atom of His35, the O2D and O3D of the nicotinamide ribose interact with OG1 of Thr100, and the main-chain oxygen atoms of Ala124 and Gly98 form hydrogen bonds with the N7N of the nicotinamide amide group (Fig