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MOTS-c Reconstitution Math MOTS-c - common doses at common vial sizes Vial Size 5 mg BAC Water 1.0 mL Concentration 5 mg/mL 5 mg Dose 1.0 mL (100 units) 2.5 mg Dose 0.50 mL (50 units) 1 mg Dose 0.20 mL (20 units) 200 mcg Dose 0.04 mL (4 units) Vial Size 5 mg BAC Water 2.0 mL Concentration 2.5 mg/mL 5 mg Dose 2.0 mL (200 units*) 2.5 mg Dose 1.0 mL (100 units) 1 mg Dose 0.40 mL (40 units) 200 mcg Dose 0.08 mL (8 units) Vial Size 10 mg BAC Water 1.0 mL Concentration 10 mg/mL 5 mg Dose 0.50 mL (50 units) 2.5 mg Dose 0.25 mL (25 units) 1 mg Dose 0.10 mL (10 units) 200 mcg Dose 0.02 mL (2 units) Vial Size 10 mg BAC Water 2.0 mL Concentration 5 mg/mL 5 mg Dose 1.0 mL (100 units) 2.5 mg Dose 0.50 mL (50 units) 1 mg Dose 0.20 mL (20 units) 200 mcg Dose 0.04 mL (4 units) Vial Size 10 mg BAC Water 3.0 mL Concentration 3.33 mg/mL 5 mg Dose 1.50 mL (150 units*) 2.5 mg Dose 0.75 mL (75 units) 1 mg Dose 0.30 mL (30 units) 200 mcg Dose 0.06 mL (6 units) * Volumes above 100 units exceed a standard 1 mL insulin syringe

Potential allergens were identified via proteomics based on structural similarity

Table 2 shows the Recovery percentage of recovered molecules from ensemble docking (%), which represents the percentage of molecules that were selected from the ensemble docking procedure calculated over the number of molecules that entered, due to the fact that some molecules have had a poor XP Gscore so the ensemble docking was not reported by Glide, as they may or may not even have been able to fit into the active site of the receptors

Something interesting can happen if a layer of impermeable rock sits above a layer of water-filled permeable rock, and if the impermeable rock slopes downward