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In contrast, the FREEDOM trial reported that the constant infusion of exenatide (20 ug daily for 3 months followed by 60 g daily) through an osmotic minipump was non-inferior to the placebo in 4156 T2DM patients (with a median follow-up of 16 months) (Ruff et al

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GLP-1 refers to a class of medications that mimic the glucagon-like peptide-1 hormone to help regulate blood sugar and support weight loss

Published in Nature Medicine , the BARI-STEP trial, led by Dr Janine Makaronidis at the UCL Centre for Obesity Research, looked at use of semaglutide at a dose of 2.4mg in patients who had not responded well to bariatric surgery