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A recent Phase III clinical trial focused on gout patients who were intolerant or contraindicated to xanthine oxidase inhibitors (XOIs) revealed that lesinurad monotherapy at a dosage of 400 mg led to a significant incidence of elevated serum creatinine
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If you have been taking metformin but your blood sugar levels are still uncontrolled, or you want additional benefits such as weight reduction, cardiovascular risk reduction, or kidney protection, semaglutide alone or as a combination therapy with metformin is suitable for you
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