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Safety of Ustekinumab in inflammatory bowel disease: pooled safety analysis through 5 years in Crohns disease and 4 Years in ulcerative colitis

doi: 10.1016/j.canlet.2016.03.029 451 MaliPYangLEsveltKMAachJGuellMDiCarloJEet al

The denial letter will likely state that the medication is not medically necessary for the diagnosed condition (e.g., obesity) or that it's being used for a non-covered service (cosmetic weight loss, in their view)

The trial evaluated once weekly cagrilintide doses in participants with overweight or obesity and reported dose dependent reductions in body weight at 26 weeks, with the paper describing the treatment as well tolerated in the study setting