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The phase 3b trial, led by Weill Cornell Medicine and NewYork-Presbyterian, enrolled patients from the SURMOUNT-5 study and represents the first head-to-head data on longer-term weight maintenance using an oral GLP-1 following injectable therapy

These effects suggest Epithalon may help counteract immunosenescence and restore robust immune surveillance in aging subjects

Also in this study, this short-term treatment was well tolerated [48]

Starting a GLP-1 medication in this context requires transparent monitoring for whether nausea, diarrhea, or abdominal discomfort is baseline post-surgical variation or a medication response