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Studies also indicate that the activation patterns of particular brain regions in patients with depression, especially during emotion and reward processing, are strongly associated with gene expression patterns

References Iranmanesh A, Lizarralde G, Veldhuis JD

doi: 10.1074/jbc.274.5.2601

The GH-axis stacks (CJC-1295 / Ipamorelin combinations) have some human biomarker data, but outcomes and long-term risk tradeoffs are commonly oversold