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this is consistent with a protective effect of GLP-1 RAs on both short and long time-scales

As more patients on long-term GLP-1 therapy are followed over time, prospective research is expected to characterize the prevalence, severity, and progression of foot fat pad atrophy in this population

Wink L, Adams R, Wang Z, Klaunig JE, Plawecki MH, Posey DJ, McDougle CJ, Erickson CA (2016) A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder

Thus, mitochondria also contain a large number of antioxidants (proteins and enzymes), including glutathione, glutathione reductase, peroxiredoxin, and superoxide dismutase (Yang et al., 2020)