Introduction Thyroid diseases are the second leading cause of endocrine disorders ( Yersinia enterocolitica ), and syndromic conditions such as Down syndrome and Turner syndrome are associated with autoimmune thyroiditis ( Glyphosate is a very effective, non-selective and post-emergent herbicide used to control harmful weeds for several crops ( In this context, the objectives of this review are discuss the critical points in the regulation of HPT axis and thyroid hormones levels balance, which may be susceptible to the toxic action of glyphosate and glyphosate-based herbicides, correlating the molecular mechanisms involved in glyphosate toxicity described in the literature that may, directly or indirectly, be associated to the higher incidence of thyroid diseases
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