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When cagrilintide is paired with semaglutide as CagriSema, the gap narrows23% for CagriSema versus 25.5% for Zepbound in a direct head-to-head trialbut Zepbound still holds a modest edge

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In some embodiments, the triglycerides in any one of the otic formulations and compositions described herein are replaced with at least one of the following components in the corresponding amounts of triglyceride in the formulation or composition disclosed herein: mineral oil or any corresponding higher alkanes