Combined NNMT inhibitor treatment with reduced-calorie diet achieved 6.3 g cumulative weight loss versus 2.9 g with diet alone, and fat mass reduction was ten-fold greater with treatment (~29.3%) compared to diet switch alone (2.9%), while restoring fatty liver profiles to lean-control levels (Sampson et al., 2021)
Most evidence so far is preclinical (cells/animals), but the story is consistent: free up resources systems run smoother
What It Targets Our Epithalon peptide is designed to target: Telomere attrition and genomic instability, key hallmarks of biological aging that correlate with agerelated disease risk. Agerelated decline in melatonin production and circadian rhythm amplitude that affects sleep quality, mood, and hormonal balance. Biomarkers and symptoms of aging such as reduced recovery, low resilience to stress, and tired but wired sleep patterns in midlife and beyond. Clients already focused on longevity who want to explore precision protocols that connect peptides, telomere testing, and lifestyle design
Low dose naltrexone (again-alone!) resulted in significant clinical improvement in 75% of these patients, with complete remission noted in 25%