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[323] found that oral administration of turmeric-derived nanoparticles with a specific population (TDNPs 2) in a mouse colitis model could improve gut inflammation and accelerate the resolution of colitis by regulating the expression of proinflammatory cytokines TNF-, IL-6 and IL-1 as well as the antioxidant gene HO-1

This is executed by nullifying the pRb and free flow of the family of transcription factors (E2F), allowing the cell cycle progression from the G1 position [117119]

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