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Spectra within a precursor mass range of 6006,000 Da with a minimum MS1 signal-to-noise ratio of 25 were retained

Calleja-Gonzlez, J

INTRODUCTION Melasma is an acquired, chronic, and recurrent form of hypermelanosis, which is characterized by symmetrical brown macules and patches of variable darkness on sun exposed areas of the body, typically occurring on the face (lower cheeks, forehead, nose, and upper lip).[] Though the pathogenesis of melasma is unclear, factors such as genetic makeup, ultraviolet (UV) radiation, pregnancy, and hormonal therapy are known to influence the development of melasma

Chiou CC, Groll AH, Walsh TJ