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But her BMI crossed 32 after two pregnancies and a desk job, and when her sister lost 40 pounds on the medication she figured, worth a shot

A standard 1ml insulin syringe cannot hold that volume

The primary mechanisms include: Enhanced insulin secretion in a glucose-dependent manner, helping to regulate blood sugar levels Suppression of glucagon release , reducing hepatic glucose production Delayed gastric emptying , which prolongs the feeling of fullness after meals Reduced appetite through central nervous system effects on satiety centres in the hypothalamus These combined actions lead to decreased caloric intake and, over time, significant weight reduction

Eli Lilly is also testing a strong GLP-1 injection, retatrutide, which in a clinical trial helped patients lose 17% of their weight in 24 weeks