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The therapeutic role of GSH in NAFLD As already mentioned, oxidative stress is a pathophysiological hall-mark of metabolic liver disease ( While several clinical studies examined the favorable effect of reduced GSH short-term or long-term administration on alcohol-induced liver diseases (Table 1-, and the studies at hand are to be considered pilots ( Table 1 Main studies on the role of reduced glutathione (GSH) treatment in patients with metabolic liver disease

In addition, GHSR plays critical role in the modulation of stress and anxiety 5,6 and the regulation of dopamine signaling and thus reward pathways in the CNS 7,8

10 Trans-epidermal water loss

risk factors [#1/2] Requisite risk factor is a causative drug : Chronic acetaminophen is the most common cause