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Fourth, although our data represent a diverse population, findings may best apply to the USA and have more limited applicability to international settings

Efficacy and expected weight loss Clinical trial results suggest both drugs help people lose significant weight compared to lifestyle alone, with many patients seeing double-digit percent weight loss over months

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Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial