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Antioxidant as an adjunct to root surface debridement have improved the periodontal therapy outcome in periodontitis patients by overcoming delayed wound healing induced by imbalance in redox status

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Similarly, the significant increase in GST concentrations in periodontitis patients is probably related to their catalyzing role in detoxification of xenobiotics derived from periopathogens, and neutralization of hydroperoxides derived from the lipoperoxidation process related to OS caused by the periodontal inflammatory process, in conjunction with glutathione