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These results suggested that keloid fibroblasts underwent pro-senescence regulation earlier compared with normal skin fibroblasts via p53-pS15 under serum limitation stimulus, and p53-pS15 and FOXO4 translocated from the nucleus to the cytoplasm during FOXO4-DRI treatment

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This coenzyme is required as hydrogen donor for reactions of various biochemical pathways as well as for the stability of catalase and the preservation and regeneration of the reduced form of glutathione

Using the supplement after this date may reduce its effectiveness