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Patients should also contact their healthcare provider if constipation significantly impacts quality of life or medication adherence, as dose adjustment or alternative GLP-1 receptor agonist formulations may be considered

During follow-up, providers evaluate pain scores, neurological function, quality of life, and overall treatment tolerance

Lancet (2017) 391:54151.10.1016/S0140-6736(17)33102-1 42 BredenoordAJChialHJCamilleriMMullanBPMurrayJA

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