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[13] [14] This cardiovascular profile has been extensively studied, with certain agents (liraglutide, semaglutide, dulaglutide) demonstrating cardiovascular outcome benefits in patients with established cardiovascular disease or multiple risk factors

This activation leads to increased insulin production, reduced appetite, and support for weight loss

This stepwise approach minimizes side effects and helps identify the lowest effective dose of each medication

Investigations may include blood pressure measurement, cardiovascular risk assessment, fasting glucose/HbA1c, lipid profile, and morning total testosterone (which may be repeated if low)