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In conclusion, GLP-1R activation triggers a series of complex physiological responses in pancreatic -cells that work together to increase insulin secretion, inhibit -cell apoptosis and stimulate proliferation, protect -cells and ultimately regulate blood glucose

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PMID: 27532814

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However, both SIRT levels increased with the decrease of ROS level after treatment with the antioxidant glucagon-like peptide 1 analog, exendin-4 (EX4) (56)

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Scar tissue replaces follicles permanently

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