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The commercial price of D-allulose is expected to approach the prices of competing sugar-substituting sweeteners, such as xylitol (US $25/kg), mannitol (US $15/kg), and sorbitol (US $110/kg)

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Triggered by ghrelin receptor activation Can lead to unintended fat gain if unmanaged Typically subsides slightly over time MK-677 significantly increased appetite due to its ghrelin-mimetic properties, making it a double-edged sword for body composition. Patel et al., The Journal of Clinical Endocrinology & Metabolism 2

[1] [8] These symptoms are typically most pronounced during treatment initiation or dose escalation and often improve over time as the body adapts