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E-cigarette manufacturers, including Juul, were required to submit their products to the FDA to review by September 2020 but were able to sell products while the FDA review was underway

Based on synteny analysis, 14 NtIDDs were identified involved in segmental and/or WGD duplications, and 12 NtIDDs were classified as dispersed duplications

2 These effects and risks are more likely to occur with longer use and higher dose use, and some may result in long-term disability or carry long-term consequences