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doi: 10.1111/j.1365-3164.2006.00551.x

Protein expression was detected using an enhanced chemiluminescence (ECL) kit (NCM Biotech, Suzhou, China) and a ChemiDoc XRS System (Bio-Rad, CA, USA)

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If Achilles tendinitis is left untreated, it may cause: Severe pain Trouble walking or exercising Deformation of the tendon or heel bone Total tear or rupture of the Achilles tendon Risk Factors The common risk factors that may cause Achilles tendinitis include: Sports and Exercise Insufficient warming up before exercise Poorly-fitting footwear while running Running on uneven surfaces or uphill Quickly changing your speed Sports such as football, baseball, volleyball and tennis Certain medication Glucocorticoids Fluoroquinolones Symptoms You may see a swelling at the point of maximal tenderness along the Achilles