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One possible explanation is that GLP-1 medications affect areas of the brain involved in appetite, reward, and mood

Protocol 1: Core perimenopause support (all women) Goal: Address fundamental hormonal and metabolic changes Foundation stack: CJC-1295: 150-200mcg before bed Ipamorelin: 150-200mcg before bed BPC-157: 250mcg twice daily Selank: 300mcg intranasal, 1-2x daily as needed Why this stack: CJC + Ipamorelin: Restore GH, metabolism, sleep, energy BPC-157: Heal gut, reduce inflammation Selank: Manage mood swings and anxiety Schedule: Morning: BPC-157 250mcg, Selank 300mcg (if using) Evening: BPC-157 250mcg Before bed: CJC-1295 + Ipamorelin 150-200mcg each Duration: 6-12 months minimum (throughout perimenopause transition) Expected benefits: Better energy and vitality Improved sleep quality Maintained metabolism Reduced inflammation Stable mood Overall improved quality of life Cost: $300-450/month See our peptide stacks guide , can you cycle different peptides , and peptide cycle planning guide