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Radiotherapy resistance in advanced PCa arises from multifactorial mechanisms, including enhanced DNA repair, cancer stem cell (CSC) persistence, immunosuppressive TME, and metabolic reprogramming [72,73]

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McElya at Neighborhood Medical Center: - Decreased appetite and reduced cravings - Enhanced energy levels - Improved mood and mental clarity - Increased lean muscle mass - Improved recovery and endurance during physical activity Safety and Considerations Before starting any therapy, it's essential to consult with a healthcare professional to discuss options and potential side effects

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