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(More information) Several methodological issues (e.g., tests used to assess cognition, choice of study population, nature of the supplementation, study duration, etc.) may have contributed to the conflicting results observed in intervention studies

This deficiency was particularly pronounced in individuals with treatment-resistant depression and those with a history of emotional neglect

The authors compile data showing GHK-Cu modulates expression of more than 4,000 human genes including substantial upregulation of antioxidant defense genes, DNA repair genes, and genes encoding collagen and elastin biosynthesis enzymes while downregulating pro-inflammatory and tissue-degradation pathways