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Using research-grade products intended for laboratory work exposes users to unnecessary risks including contamination, incorrect dosing, and potential adverse reactions

The brain is particularly vulnerable to oxidative stress due to its high oxygen consumption, abundant polyunsaturated fatty acids, and relatively modest antioxidant defenses compared to other organs [1][2][48]

JamilianHJamilianMSamimiMAfshar EbrahimiFRahimiMBahmaniFet al

Over the years, methods have been refined into the most commonly used protocol today, which uses an acid/ethanol precipitation (to disrupt the IGF-1/IGFBP complex) followed by the addition of insulin-like growth factor-2 (IGF-2) to prevent the reformation of the IGF/IGFBP complex