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While your body makes its own supply, certain health challenges can drain those levels faster than you can replenish them

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The GIPR missense variant, rs1800437, has been associated with a large number of traits in the public domain, including BMI and body mass phenotypes, T2D, blood glucose and a number of metabolic or haematologic traits including blood pressure, reticulocyte and/or erythrocyte volume and urinary calculus (Supplementary Table 18)

Effect of vitamin C on endothelial function in health and disease: a systematic review and meta-analysis of randomised controlled trials