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Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study

For example, L-carnitine is removed from the circulation during hemodialysis

Estrogens influence on ER in the prefrontal cortex modulates the strength of synaptic connections and neuronal excitability, enhancing cognitive flexibility and processing speed [13,20,21]

In this study we employed structure-based site-directed mutagenesis together with pharmacological assays to compare agonist efficacy across two key signaling pathways, cAMP accumulation and ERK1/2 phosphorylation (pERK1/2)